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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13410 |
ZLDI-8
|
Apoptosis; Phosphatase; Gamma-secretase; Immunology/Inflammation related | Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome; Stem Cells |
ZLDI-8 是 Notch 激活/裂解酶 ADAM-17 的抑制剂,可抑制 Notch 蛋白裂解,并降低促存活/抗凋亡和上皮-间质转化相关蛋白的表达。它还是竞争性不可逆酪氨酸磷酸酶抑制剂,以IC50为 5.32 μM 抑制 MHCC97-H 细胞的生长。 | |||
T73998 |
ADAM8-IN-1
|
||
ADAM8-IN-1 是一种有效的ADAM8抑制剂,其IC50值为 73 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03877 |
ADAM8/CD156a Protein, Rhesus, Recombinant (His)
ADAM metallopeptidase domain 8 |
Rhesus | HEK293 Cells |
ADAM8/CD156a Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.6 kDa and the accession number is XP_002805919.1. | |||
TMPK-00933 |
ADAM8/CD156a Protein, Mouse, Recombinant (His)
CD156a,MGC134985,ADAM 8,Ms2,A... |
Mouse | HEK293 Cells |
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/... | |||
TMPK-00918 |
ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)
CD156a,ADAM 8,MGC134985,Adam<... |
Human | HEK293 Cells |
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/... | |||
TMPY-05532 |
ADAM8/CD156a Protein, Human, Recombinant (His)
CD156,MS2,CD156a,ADAM metallopeptidase domain 8... |
Human | HEK293 Cells |
ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is Q14C66. | |||
TMPY-04123 |
CEACAM1 Protein, Human, Recombinant (His & hFc)
CEACAM‑1,carcinoembryonic antigen-related cell adhesion mole... |
Human | HEK293 Cells |
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8. | |||
TMPJ-00808 |
CD45RA Protein, Human, Recombinant (His)
PTPRC,CD45R,CD45,LCA,protein tyrosine phosphatase, receptor ... |
Human | HEK293 Cells |
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8. | |||
TMPH-01705 |
Mucin-1/MUC1 Protein, Human, Recombinant (His)
|
Human | E. coli |
Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8. | |||
TMPJ-00828 |
Tau-F Protein, Human, Recombinant
Neurofibrillary tangle protein,Paired helical filament-tau,M... |
Human | E. coli |
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def... | |||
TMPY-00717 |
CEACAM1 Protein, Human, Recombinant (His)
CEACAM‑1,BGP1,BGP,carcinoembryonic antigen-related cell adhe... |
Human | HEK293 Cells |
CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8. | |||
TMPY-06707 |
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)
ADMCKD,PEMT,KL-6,ADMCKD1,H23AG,mucin 1, cell surface associa... |
Human | HEK293 Cells |
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8. | |||
TMPJ-01330 |
CD299 Protein, Human, Recombinant (His & Flag)
DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami... |
Human | HEK293 Cells |
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso... | |||
TMPY-00668 |
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
CTFγ,amyloid beta (A4) precursor protein,AAA,ABPP,CVAP,APPI,... |
Human | HEK293 Cells |
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8. |